This is a good introduction to rational design of biological systems, but its target audience appears to be investors in biotech, with scientists working in the field only of secondary interest.
Carlson is an engineer with a background in aeronautical engineering. He is currently the CSO of biodesic, a company working on bacterial production of biodiesel suitable for fuel. His belief in the power of engineering principles as applied to biological systems is infectious, one would hardly expect less, but he goes overboard in his insistence that rational design of complex biological systems is possible NOW, if only biologists were replaced by engineers.
*Must go to work, but will finish review later*